| MANIFESTATIONS
OF NEUROTOXICITY |
| AXONOPATHIES |
|
|
|
|
|
|
|
|
|
| • | Primary site of
toxicity is axon |
|||||||
| • | Degeneration of
axon, surrounding |
|||||||
| myelin, but cell
body remains intact |
||||||||
| • | Irreversible in
CNS, but reversible in |
|||||||
| PNS |
||||||||
| • | Caused
by CS2, acrylamide, gold, |
|||||||
| organophosphorous
esters |
||||||||