Some XP proteins are
• XPA, which encodes a protein that binds the
damaged site and helps assemble the other
proteins needed for NER.
•  XPB and XPD, which are part of TFIIH. Some
mutations in XPB and XPD also produce signs of
premature aging.
• XPF, with ERCC1 cuts the backbone on the 5'
side of the damage
• XPG, which cuts the backbone on the 3' side.
• XPC interacts with HR23B in GGR and recognizes
damage
• XPD is a DNA helicase in in transcription complex
• VPV is a by-pass polymerase