| DNA repair diseases |
|
|
|
|
|
|
|
|
|
|
| HNPCC |
|||||||||
| • | Heriditary
nonpolyposis colorectcal cancer |
||||||||
| • | Autosomal
dominant, multigenic, up to 1/200 |
||||||||
| • | Symptoms: |
||||||||
| – | High frequency of colon and several other cancers |
||||||||
| • | Defect
in mismatch repair |
||||||||
| ©1999
Lee Bardwell |