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| Nucleotide Excision |
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| Repair |
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| • | Carried
out by a multi-protein complex |
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| • | Removes
bulky adducts from DNA, e.g. |
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| – | Pyrimidine
dimers caused by UV |
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| – | Benzopyrene-DNA
adducts |
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| • | Nearby
nucleotides are also excised |
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| • | Resulting
single-strand gap is filled in by |
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| polymerase |
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| ©2000
Lee Bardwell |