Postexposure Management for HCV
n IG, antivirals not recommended for prophylaxis
n Follow-up after needlesticks, sharps, or mucosal
exposures to HCV-positive blood
– Test source for anti-HCV
– Test worker if source anti-HCV positive
• Anti-HCV and ALT at baseline and 4-6 months later
• For earlier diagnosis, HCV RNA at 4-6 weeks
– Confirm all anti-HCV results with RIBA
n Refer infected worker to specialist for medical
evaluation and management