Mifepristone: Efficacy
• Glasier, et al, 1992
– 800 women and adolescents
– Single 600 mg dose given within 72 hours of unprotected
coitus was 100% effective
• WHO 1999
– 1,700 women
– 10 mg and 50 mg mifepristone equal in efficacy to 600 mg
dose (85% decrease in number of pregnancies estimated
to occur without treatment)
– Effective up to 5 days after unprotected sex
Glasier A, et al. N Engl J Med. 1992;327(15):1041-1044.
Task Force on Postovulatory Methods of Fertility Regulation.
Lancet. 1999;353:697-702.