Serotonin 5-HT1A Receptors
• Major part of serotonin communication in brain.
• Both an autoreceptor and a terminal field post-
synaptic receptor.
• Role hypothesized in the pathobiology of mood
disorders.
• Role hypothesized in the action of antidepressants.
• Can be studied in postmortem brain and in live
patients using PET scanning.