Hypothalamus  and Limbic System:
Clinical Context (cont.)
– Fever
• Need to detect temperature changes and modulate the autonomic
nervous system to either retain or dissipate heat.
– Addiction
• Many recreational drugs work through neural pathways involved in
reward and motivated behavior that form an important part of limbic
system function.
– Anxiety Disorders
• Many anxiety disorders, such as Panic Disorder and Post-traumatic
stress disorder have physiological symptoms mediated by the
autonomic nervous system and by the limbic system.
– Obesity.
• Feeding behavior is in part controlled by the hypothalamus, and
interactions between limbic reward circuitry and the hypothalamus
are important to feeding behavior.