What hypothalamic pathways
influence endocrine function?
• The hypothalamus controls the
endocrine system by secreting
oxytocin and vasopressin into
the general circulation from
nerve terminals ending in the
posterior pituitary (5 in figure).
• The hypothalamus also
secretes regulatory hormones
into local portal circulation that
drains into the anterior pituitary
(3 and 4).
• Finally, some hypothalamic
neurons influence peptidergic
neurons, synapsing at those
neurons cell bodies or axon
terminals (1 and 2).