Neural Input and Hormonal Output:
oxytocin release and lactation
• Supraoptic and paraventricular nuclei contain
magnocellular neurons that secrete oxytocin into
the general circulation in the posterior pituitary.
• When a baby sucks on a mother’s nipples,
mechanoreceptors are stimulated.  These
receptors activate neurons that project to the
magnocellular hypothalamic neurons, causing
those cells to fire brief bursts, releasing oxytocin.
• Oxytocin, in turn, increases contraction of
myoepithelial cells in the mamillary glands,
leading to milk ejection.