| THE SPACING
RULE |
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| • | RXR
heterodimers bind direct repeats of specific half sites. |
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| • | The direct
repeats are separated by different numbers of nucleotides |
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| n=1; DR-1 |
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| n=2; DR-2 |
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| etc. |
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| • | Different
heterodimers bind to different HREs depending on the value of n |
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