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| CHIP Assay -- Chromatin
Immunoprecipitation |
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| • | Cross-link
protein and DNA with formaldehyde |
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| • | Shear DNA |
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| • | Using antibody
against protein (or modification) of |
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| interest, immunoprecipitate protein-DNA
complex |
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| • | Use heat to reverse cross-link |
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| • | Amplify specific
DNA by PCR |
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