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| Calcium Dependent Gating |
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| of
P/Q Ca2+ Channels |
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| • | Kinetics
of inactivation and facilitation differ |
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| from L-type
channel gating |
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| • | Calmodulin appears to be the Ca2+ sensor |
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| and
the IQ motif is one effector domain in a1A |
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| • | CBD
may be another effector domain |
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| • | The Ca2+-binding protein CaBP1 regulates |
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| inactivation
in a Ca2+-independent manner |
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